Boost Fund: Bifunctional Fusion Proteins for Plant Protection

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Reducing usage of pesticides and fungicides is of high importance for a sustainable bioeconomy and insect pests and microbial pathogens are major causes of crop losses worldwide which sum up to losses of about 500 billion US-Dollars per year. The BiFuProts project aims to develop a broadly applicable bifunctional platform of fusion proteins for pest management and reduced use of fungicides. Bifunctional fusion proteins are composed of a plant leaf anchoring peptide and an antimicrobial peptide for pest management. Starting point for the BiFuProts-technology development are three crop plants like soybean, corn, and barley and as targets for the antifungal peptides the phytopathogenic fungi. In total five antimicrobial peptides in combination with ten selected anchoring peptides will be generated and one anchor peptide per crop plant will be optimized for stronger/long-lasting binding on plant leaves. Characterization of rain fastness and deposition properties on leaves will ensure a demand matching technology platform development and contribute through reduced use of fungicides to the general aim of the Bioeconomy Science Center for a sustainable and integrated bioeconomy in which discipline boarders are bridged and innovative solutions developed.

The scientific activities of the Bioeconomy Science Center were financially supported by the Ministry of Innovation, Science and Resesarch within the framework of the NRW Strategieprojekt BioSC (No. 313/323‐400‐002 13).